Archive for the ‘immune disease’ Category
January 19th, 2011 | 
Author: An immune system is a system of natural and organic structures and processes within an organism that protects against disease by identifying and killing pathogens and tumor cells. The immune system defends and holds the organisms of infection with layered defenses increasing specificity. Even simple physical barriers prevent pathogens such as bacteria and viruses enter the body. In modern times are the subject of a revolution combinations drink recipe. Regular fruits such as bananas, strawberries, peaches, and are not the only additions in these healthy drinks used. The choice of the most popular fruit is often used the Mangosteen. This is due to an increased risk of infestation. This is the same size of a small apple and white on the inside contains a nice variety in pieces like a tangerine. In any case, fans of fruit in a position available with the product of fruit juice or capsule form. Mangosteen is a tropical fruit in Southeast Asia.
The fruit of the Noni tree has powerful antioxidants, the mood that include improving the immune system and improved features in India and the Pacific Islands. Another interesting thing, and is used in the noni smoothies. The scientists suspect that it is a scavenger. This fruit comes from South Asia. The scientists suspect that it is a scavenger. Noni Morinda or important Citrufolia has cancer and can reduce tumor growth and immune system. The acai berry is rich in fiber and is believed to have properties that the body free of toxins. Research in this field emission properties of the berry, and for promoting a practice, well being and reduce inflammation. The acai berry and tropical parts of Central America and South is a different mix of vitamins Smoothie mix. This fruit is the size of grapes and a blue-reddish brown.
Blueberries also have properties to prevent chronic diseases. Rich in vitamin C and E are blueberries a good choice to mix and anthocyanins and phenolics that contain a strong anti-oxidative properties mentioned. These three components are added tropical, a form you can consume your personal development. These are drugs to complement, and in combination with blueberries.
Blueberries can be found more easily, other fruits and berries are not readily available. Therefore, a tropical fruit mixed with combinations of these fruits is an excellent proposal to enrich a healthy lifestyle. Some of these fruits are processed into juice or powder, which can be added to a malt beverage found.
Increase energy levels can improve the social welfare system that allows them to be more productive throughout the day. Strengthening of the fruit elevator merged Vita-Mix full of antioxidants powers are sufficient reasons for what they want. A positive dynamic personality learns to reject negative thoughts and destructive, or at least minimize their impact. This leads to better performance in all aspects of life. If a person is attracted to, they feel the world have. This leads to a better mental attitude, depression, which can interrupt their work.
Therefore, you build your immune system by antioxidants in these foods, fruits, vegetables, fruit, or help you feel good.
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The rainy season coincides with the onset of various diseases, including influenza. Some people seem more immune to the flu virus, while others are sneezing, coughing and a stuffy nose. According to experts, the immune system was affected by various unforeseen patterns, such as the amount of sugar consumed. We find the factors that affect our immune system. Eating too much sugar not only cause fat deposits. The study in the American Journal of Clinical Nutrition published words, kill by eating 100 grams of sugar (about 3 cans soda) the ability of white blood cells, bacteria during the next 5 hours will be reduced.
Our body needs water to remove toxins. more or less water, we take each person differently, depending on the activity and the environment. To find out if you drink enough, you look at the color of your urine. If the color is yellow, means you have enough to drink.
Losing weight is too much is bad for the heart, brain and immune system. Obesity leads to a disturbed hormonal balance and disrupt the ability to fight infection, the inflammatory immune cells.
Mucus / mucous membranes of the nose is used to contract the virus and prevents the entry into the body. If your nose is often dry, the viruses and bacteria to enter freely.
It is no coincidence that suddenly flu after the important work deadlines. According to a study by the American Psychological Association has published long-term stress weakens the immune system response. Stress is worse and the symptoms of influenza.
The average adult has a cold 2:59 times a year. If you often have the flu, your immune system is not functioning optimally, ie.The good quality of sleep, exercise and consumption of nutritious foods to improve the immunity of the body.
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Though many people have not even heard of Lupus, it is common – more common than some well-known diseases such as multiple sclerosis, muscular dystrophy and leukemia. But because not much is known about the disease, treatment of lupus is made more difficult. What is lupus, exactly?
Diagnosis and treatment of lupus(http://www.mitamins.com/disease/Lupus.html) is made more complicated by the fact that currently, there is no one single test that can positively identify the disease. In fact, lupus is often mistaken for other diseases with some similar symptoms, such as multiple sclerosis or arthritis. In fact, lupus is an auto-immune disease in which the body essentially “turns” on itself. When this happens the body creates antibodies that attack the body rather than protect it.
Lupus(http://www.mitamins.com/disease/Lupus.html) sometimes only affects a single area of the body. Some of the most common areas to be affected are:
# Lungs: lupus can cause inflammation of the lungs’ lining, which can lead to pneumonia or pleuritis
# Kidneys: Inflammation of the kidneys can be caused by lupus, and this inflammation can lead to nephritis. The onset of nephritis is usually not accompanied by pain, so the lupus may not be detected.
# Heart: Chest pains, and subsequent hardening of the arteries, may be caused by lupus
# Blood: Anemia and inflamed blood vessels can result from lupus.
Lupus can often be identified by a rash on the body, most often on the face. Sunscreen can help to treat this rash. Some medications for other illnesses can trigger attacks, so this should be kept in mind in the treatment of lupus. Flu shots are recommended for lupus treatment, as they can prevent secondary infections which commonly occur in those with lupus. Other suspected triggers of lupus are dental fillings and hair dye, though there is no conclusive evidence of this. Because fear and anxiety may be triggers of lupus attacks, discontinuing use of certain products believed by patients to trigger attacks may be beneficial, even if these substances do not truly affect the body physiologically.
Natural Treatment of Lupus(http://www.mitamins.com/disease/Lupus.html)
A healthy diet containing necessary vitamins and nutrients, as well as regular exercise, are most effective in the prevention and treatment of lupus. Other kinds of meditative or calming activities, such as breathing exercises, can be effective in lupus treatment and can prevent skin flare-ups.
If you are a celiac, your miracle cure is under way – being trialed in Melbourne Australia from April 2009! It could conceivably desensitize people with celiac disease to the point that the villi in their small intestine are not damaged by the gluten protein. However with the need for extensive testing in this three phase trial, the vaccine may not be ready for release for several years.
Before we go into the details of such a cure it should be noted that this vaccine might not be a â??magic bullet’ that makes people permanently immune to the gluten protein, it might ‘only’ desensitize them. Also be aware that if you choose to undertake the â??therapy’ there are no guarantees of how you will react, and the only way to regularly check to see if you have been â??cured’ would be regular intestine biopsies. As it is known that some people take over two years to heal their intestines from gluten damage, how risky will this strategy be? It is expected that testing will be extensive so these questions may all sit under the â??devil’s advocate’ category, and all may be well.
An even more philosophical question is what effect covering up the cause of your disease will have on your body. Books have been written that suggest that it is the increased gluten potency in wheat and other gluten grains as well as increased use in manufactured foods that has led to an overdose of gluten. Our bodies then pass a â??tipping point’ where our genetic predisposition to CD turns into an active disease. If this is true, how wise would it be to continue ingesting unnaturally high levels of gluten, once â??cured’ just because we can? Sure it would make life simpler not following a gluten free diet, however maybe we should wait for gluten to be decreased at the source, the growing fields, before we return to a gluten filled diet.
Different types of celiac disease identified
With all these issues under consideration, I am sure that every celiac would still be interested in a â??cure’. A July 2007 article based on research conducted in Victoria, Australia, showed that “Celiac disease – is strongly associated with human leukocyte antigen (HLA) DQ2 and to a lesser extent with HLA DQ8.”
“HLA genes are part of the major histocompatibility complex (MHC), which plays a pivotal role in the immune system. HLA-DQ2 mediated celiac disease is common in people of European ancestry, with about 90 per cent of sufferers positive for DQ2. Another five per cent possess HLA DQ8. In China and East Asia, DQ2 genes are rare while DQ8 genes are as common as in Europe.”
So it appears that this preliminary research has been able to isolate two main versions of celiac disease. However the molecular workings of the immune response in the two antigens appear to be very different. The researchers discovered that T-cells in people with DQ8-associated celiac disease reacted quite differently to the small proteins in gluten than the T-cells in people with the DQ2 form of the disease.
“At the moment a gluten-free diet is the only treatment for celiac disease but nearly half the people on the diet still have damage to their small intestine. Consequently other therapies, including a vaccine and three different drugs, are in various stages of development. The research team believes celiac disease might be the first example of an immune disease where treatments are customized according to the genetic make-up of the patient.”
The celiac vaccine discovery
The discovery that lead to the creation of the vaccine was that the one critical part of wheat gluten protein that was toxic was the common genetic version (HLA DQ2) of celiac disease. “As much as the identity of the toxic component of gluten was important, it was the way in which it was found that has proven to be even more important. By eating gluten in wheat, rye, or barley for three days (even a single meal will suffice in some people), immune cells (T cells) that damage the small intestine are mobilized into blood for a few short days. The T cells in blood can be monitored and analyzed to define what part of gluten they recognize. The parts of gluten recognized by the vast majority of T cells involved in celiac disease can be condensed to a few “short” fragments of gluten that remain after its digestion in the gut. These gluten fragments can be synthesized using fairly standard chemistry and are the basis for the celiac vaccine.”
The Celiac Vaccine Trials
The original research began at Oxford England in 1997. The work continued in Australia in 2002 and by April 2009 Bob Anderson from the Walter and Eliza Hall Institute of Medical research (Melbourne, Australia) will commence the first world trials of a celiac vaccine that could reduce or eradicate the need for being gluten free. In fact Bob Anderson calls the vaccine a “next-generation desensitization therapy” that has been successful in mice and is soon to be tested on celiacs.
“The vaccine will be tested on 40 volunteers with celiac disease over 11 months to establish that it does not harm them. In a subsequent phase 2 trial, which is designed to find out if the treatment is effective, volunteers will receive the treatment and then be challenged with foods containing gluten. Their immune response and intestines will then be examined to see if a tolerance to gluten has developed. The therapy involves repeatedly injecting solutions of gluten at increasing concentrations. The aim is to desensitize the subjects slowly, in a similar way to hay fever and dust allergy desensitization treatments.”
Testing process
“For a new drug to be accepted for use in people in Australia, Europe, or North America it must have progressed successfully from Phase 1 (safety) studies usually involving up to about 30 volunteers, to Phase 2 (efficacy) studies to show that “it works” in people with the medical condition of interest (typically about 200 volunteers in several locations around the world), and to Phase 3 (similar to Phase 2 but involving several thousand volunteers in many sites around the world).”
The celiac vaccine future
Due to difficulties in funding, Bob Anderson (Walter and Eliza Hall Institute) co-founded a commercial company called Nexpep to develop the vaccine. Nucleus Network, Centre for Clinical Studies (CCS) in the Alfred Hospital in Melbourne, will be conducting the Phase 1 clinical trial.
The difficulty he has faced, besides the technical issues, is the low diagnosis level of celiac disease and the mass of associated symptoms has made a vaccine cure unattractive to traditional pharmaceutical companies. These companies always prefer well defined markets to accurately forecast payback periods for their R&D and marketing expenses.
The facts are that for this vaccine to prove financially viable, The US will need to approve the drug and doctors and celiacs will need to accept the treatment. One report estimates that only 600,000 people are diagnosed with celiac disease (out of the 5 million with celiac disease in North America and Europe). Â
Compounded to the funding challenges is that previously, globally, there have only been three “randomized, controlled” studies of the gluten free diet – one in children and two in adults – the largest with 57 participants.”
The assessment of the vaccine treatment will require repeated endoscopy and collection of small intestine biopsies which are expensive and un-enjoyable for volunteers. However a recent trial in Italy has shown that biopsies are still the only â??almost’ guaranteed method of assessing gluten damage. The study findings showed that “two years after adopting a gluten free diet, about half those people diagnosed with celiac disease continued to have villous atrophy as severe as when they were first diagnosed. Only about one in five of those with severe intestinal damage (villous atrophy) on a gluten free diet had raised (abnormal) blood levels of transglutaminase antibody, meaning that standard blood tests to monitor disease activity were relatively ineffective.”
So while the development of this vaccine is an important step in potentially eradicating celiac disease, philosophical questions still remain as issues for the long term efficacy of the vaccines. As an Australian first, this research is applauded by the gluten free community. We wish the researchers and medical staff all of the best in demystifying this illusive disease.
Article references are available on the gluten free pages website.Â
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The immune system of our body is a collection of cells, tissues and molecules which work together to protect the body against any attack from foreign bodies like bacteria, viruses, fungi etc. Autoimmune disease occurs when the body’s immune system fails and starts producing antibodies which react against some of the body’s own tissues. This can have a lot of effects on the body and can even prove to be fatal in many cases. It is said to be the 3rd most common disease in USA. It is said to affect one in thirty one Americans.
An autoimmune process can cause the destruction of a particular type of cell or tissue, can cause an organ to grow excessively, and can even affect the organs’ functionality. The endocrine glands are mostly affected by this kind of disease. The generally affected areas include are the red blood cells, adrenal glands, thyroid, pancreas, connecting tissues and many skin and muscle joints. Women are more susceptible to auto immune diseases than men. The reason for this is yet to be discovered by researchers.
One of the main reasons for this could be that women have great immunity when compared to men for all kinds of diseases. So this makes them more prone to auto immune diseases.
Autoimmune diseases can be classified into 2 types:
Type1: Non organ Specific.
Type 2: Organ specific.
The first type of the disease can be spread throughout the entire body. Some of the non-organ specific disorders are: myasthenia gravis, multiple sclerosis, lupus and rheumatoid arthritis.
The second type is specific to a particular organ of the body. Some of the organ specific disorders are: chronic hepatitis – a disease that affects the liver, Addison’s disease affecting the adrenal glands, pernicious anemia which affects the stomach, diabetes (insulin dependent) affecting the pancreas and Hashimoto’s disease that affects the thyroid glands.
Researchers believe that there are many factors that can be attributed as the cause of autoimmune diseases. Drugs, pollution, certain types of viruses, heredity are some of the attributed causes. Many doctors also believe that close marriages or marrying family members is also a major factor for the auto immune diseases.
Doctors conduct various tests like checking your blood samples, radiological studies etc to diagnose if you have the autoimmune disease. There symptoms accompanied by the auto immune disease are specific to each disease and widely vary. The general symptoms are fever, low grade infections, fatigue, dizziness and loss of appetite.
Most autoimmune diseases are given treatment according to the symptoms. Doctors prescribe corticosteroid drugs, non-steroidal anti-inflammatory drugs (NSAIDs) and some very powerful immunosuppressant drugs like cyclophosphamide, azathioprine and methotrexate that suppresses the response of the immune system and there by the progression of the autoimmune disease.
There is no best remedy other than self care. If one takes proper care of themselves without leading an unhealthy life these diseases can be prevented. Doctors recommend a diet highly rich in vitamins and minerals can help reduce the effects of the auto immune disease.
To Your Health!